4
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T78778 | D3R/MOR antagonist 1 | Dopamine Receptor | |
Compound 114 (D3R/MOR antagonist 1) exhibits dual antagonistic activity at dopamine D3 receptors (D3R) and mu-opioid receptors (MOR), with K i values of 46.5 nM and 691 nM, respectively. It offers analgesic benefits thro... | |||
T78779 | D3R/MOR antagonist 2 | Dopamine Receptor | |
Compound 121, a D3R/MOR antagonist with K i values of 361 nM and 85.2 nM for D3R and MOR respectively, has the potential for analgesic effects through MOR partial agonism and may reduce opioid-misuse liability through D3... | |||
T79547 | MOR agonist-2 | Opioid Receptor | |
Compound 46, designated as MOR agonist-2, serves as a D3R antagonist and a MOR agonist with respective K i values of 7.26 nM and 564 nM. This compound holds potential for analgesic effects attributed to its partial agoni... | |||
T81763 | MOR agonist-3 | ||
MOR agonist-3 (Compound 84) is a dual D3R/MOR antagonist with K i values of 382 nM and 55.2 nM, respectively. It shows promise for analgesia via partial agonism at MORs and may mitigate opioid abuse via D3R antagonism. T... |